Rapid antidepressant effects of repeated doses of ketamine compared with electroconvulsive therapy in hospitalized patients with major depressive disorder.
Ghasemi M, Kazemi MH, Yoosefi A, Ghasemi A, Paragomi P, Amini H, Afzali MH. Rapid antidepressant effects of repeated doses of ketamine compared with electroconvulsive therapy in hospitalized patients with major depressive disorder. Psychiatry Res. 2014 Feb 28;215(2):355-61. doi: 10.1016/j.psychres.2013.12.008. Epub 2013 Dec 13. PMID: 24374115. Highlights: In this blind, randomized study, 18 patients […]
Augmentation of response and remission to serial intravenous subanesthetic ketamine in treatment resistant depression.
Shiroma, Johns et al. Augmentation of response and remission to serial intravenous subanesthetic ketamine in treatment-resistant depression” Journal of Affective Disorders. 2014 Feb;155:123-9. Highlights: In this study, we determined antidepressant response and remission to six consecutive ketamine infusions while maintaining stable doses of the antidepressant regimen. We also examined the trajectory of response and remission […]
Antidepressant efficacy of ketamine in treatment-resistant major depression: a two-site randomized controlled trial.
Murrough JW, Iosifescu DV, Chang LC, Al Jurdi RK, Green CE, Perez AM, Iqbal S, Pillemer S, Foulkes A, Shah A, Charney DS, Mathew SJ. Antidepressant efficacy of ketamine in treatment-resistant major depression: a two-site randomized controlled trial. Am J Psychiatry. 2013 Oct;170(10):1134-42. doi: 10.1176/appi.ajp.2013.13030392. PMID: 23982301; PMCID: PMC3992936. Highlights: Ketamine showed rapid antidepressant effects […]
Rapid and Longer-Term Antidepressant Effects of Repeated Ketamine Infusions in Treatment-Resistant Major Depression.
Murrough, Perez, et al. Rapid and Longer-Term Antidepressant Effects of Repeated Ketamine Infusions in Treatment-Resistant Major Depression” Biological Psychiatry 2013 Aug 15; 74(4): 250–256. Highlights: In this article, there were 24 patients treated with six IV infusions of ketamine (.5mg/kg) over 12 days. Participants with TRD (n=24) underwent a washout of antidepressant medication followed by […]
