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MICRODOSING KETAMINE

Daily relief to take control of your mental health.  

Ketamine and IV Therapy

Neuroplasticity

Mental Health

Better Mood

Antidepressant

Less Inflammation

Antiinflammation

Learning

Learning

$125 per month subscription: includes rapid dissolving tablets, taken sublingually (under the tongue). The treatment includes the cost of your ketamine medication mailed to your home, as well as routine follow-ups from your provider to check in on your progress and make adjustments to your treatment plan. For some patients with higher tolerance to ketamine and need higher dosages, the cost maybe more. 

Free onboarding:  customized a patient’s dosage and program based on medical background. This includes an initial Telehealth consultation and intake designed to personalize your treatment plan and deliver your first month’s supply of ketamine to you at home.

Approximately 30%

Varies from person to person based on body weight, medical and medication history.

Overview

Microdosing with ketamine offers a cost-effective alternative to intravenous or intranasal routes.  Dosages in IV and intranasal form can potentially cause a dissociative effect or psychedelic experience.  With AVYIA’s microdosing program, we avoid dissociative and psychedelic properties of the drug by taking smaller doses on a daily or regular basis.  Recent studies indicate that microdosing ketamine is still effective in treating mental health disorders, migraines, and suicidal ideation without the dissociative effects.  Those with chronic pain may benefit from microdosing daily as patients may require less opioid narcotics while on ketamine.  

Ketamine microdosing is taken sublingually, or under the tongue, allowing direct absorption into the bloodstream through the mucosal membranes.  One of the primary benefits of taking ketamine orally is the convenience it offers to patients, negating the need for healthcare professionals to administer the drug and subsequently monitor the patient.  Those who microdose should notify their primary care or mental health providers that they are taking ketamine, so all parties can ensure safety in a patient’s care and therapeutic objectives.

While a standard microdosing regimen with ketamine provides impressive results by itself, combining it with therapy can enhance learning and yield superior outcomes.  AVYIA offers ketamine-assisted psychotherapy, where patients work with a licensed therapist during their ketamine treatments to yield better treatment outcomes.  

What does it treat?

  • Anxiety or Generalized Anxiety Disorder
  • Resistant Depression
  • Depressive Disorder
  • Post-Traumatic Stress Disorder
  • Bipolar Affective Disorder
  • Bipolar Depression
  • Post-Partum Depression
  • Obsessive Compulsive Disorder
  • Suicidal Thoughts or Ideation

Benefits of Ketamine

Ketamine is a member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group. Ketamine was originally developed as an anesthetic, but has gained interest in recent years for its success in treating various mental health disorders. Research is ongoing, but here's what we know about ketamine's effects and abilities to treat mental health disorders:

Rapid Antidepressant Effects

One of the most prominent features of ketamine when used to treat depression, especially treatment-resistant depression, is its ability to produce rapid antidepressant effects, often within hours to a few days.

NMDA Receptor Antagonism

Ketamine is an antagonist of the N-methyl-D-aspartate (NMDA) receptor, a type of glutamate receptor. This action is believed to play a role in its antidepressant effects, though the precise mechanisms are still under study.

Synaptic Plasticity Enhancement

Ketamine is believed to enhance synaptic plasticity, the ability of synapses to strengthen or weaken over time. This enhancement can promote the formation of new neural connections, which can be beneficial for mental health.

BDNF Release

Ketamine has been shown to increase the release of brain-derived neurotrophic factor (BDNF), a protein that supports the survival of existing neurons and encourages the growth and differentiation of new neurons and synapses.

Dissociative Effect

Some research suggests that ketamine may temporarily reduce the connectivity between certain parts of the brain, which might help "reset" dysfunctional brain networks seen in depression.

Anti-inflammatory Effects

There's emerging evidence that inflammation might play a role in mood disorders. Ketamine has shown potential anti-inflammatory effects that could contribute to its therapeutic benefits.

Reduction in Suicidal Thoughts

Ketamine has demonstrated a rapid reduction in suicidal ideation in some individuals, which is of particular interest for emergency psychiatric interventions.

Treatment of PTSD and Anxiety Disorders

Preliminary research suggests that, in addition to depression, ketamine may be beneficial in treating post-traumatic stress disorder (PTSD) and some anxiety disorders.

Neuroprotective Properties

There's some evidence to suggest that ketamine may have neuroprotective effects, helping to protect the brain from stress-induced damage and reduce brain injury (TBI) and Ischemia.

Mood Stabilization

Some studies have explored the use of ketamine for its rapid antidepressant effects in treating bipolar disorder and other mood disorders. Ketamine plays a role in offering mood-stabilizing benefits to mental health patients.