Ketamine can be administered through several routes, each with unique characteristics affecting absorption and therapeutic outcomes.
Ketamine Therapy
Hope in Every Dose – Relief for Mood Disorders and Chronic Pain
Ketamine Administrations
Monthly Subscription
$129/month — just $4/day
Intravenous Ketamine
$499/session
Intranasal Ketamine
$449/session
SPRAVATO prescription
$159 Telehealth fee
Intramuscular Ketamine
$429/session
Which Route of Administration is Right for You?
See Comparison of Effective Ketamine Treatment Options
| Method |  Intravenous Infusion (IV)
|
 Intramuscular Injection (IM)
|
 Intranasal Spray
|
 Sublingual Rapid Dissolve Tablet
|
|---|---|---|---|---|
| Route |  Direct administration into a vein
|
 Injection into the muscle
|
 Administration by inhaling a spray into the nostrils
|
 Under the tongue absorption through the membranes of the mouth
|
| Treatment Program |  6 times in 2-4 weeks
|
 8 times in 4-6 weeks
|
8 times in 4-6 weeks
|
 Daily or intermittent use over multiple months
|
https://www.youtube.com/watch?v=0i8hrXlUA5g
Mechanisms of How Ketamine Works in the Brain
Targets specific brain regions and neural circuits
1
“Reset” the brain’s Default Mode Network (DMN), which is often overactive in people with mood disorders. By quieting this network, ketamine disrupts negative thought loops and allows the brain to form new, healthier patterns—like a mental reboot.
2
Creates a temporary sense of detachment, allowing reprocessing of traumatic memories. Treats: Suicidal Ideation, PTSD, OCD, Existential Distress
3
Creates a temporary sense of detachment, allowing reprocessing of traumatic memories. Treats: Suicidal Ideation, PTSD, OCD, Existential Distress
4
Promotes brain repair and growth by boosting brain-derived neurotrophic factor (BDNF). Treats: Depression, PTSD, Suicidal Ideation
5
Enhances synaptic plasticity by increasing glutamate activity and strengthening neural connections. Treats: Major Depressive Disorder (MDD), Treatment-Resistant Depression (TRD), PTSD, Anxiety, Bipolar Disorder
6
Reduces inflammation in the brain caused by stress or trauma. Treats: Depression, Anxiety, PTSD, Neurogenic Pain (e.g., Fibromyalgia, CRPS)
7
Enhances serotonin, dopamine, and endogenous opioid activity to regulate mood and relieve pain. Treats: Chronic Pain (e.g., CRPS, Neuropathic Pain), Depression, Anxiety
Traditional Treatments (SSRIs, Opioids) vs. Ketamine Therapy
A breakthrough in mental health and pain management
Ketamine therapy outperforms traditional treatments in key areas:
- Speed of Action: Rapid relief within hours, unlike SSRIs that take weeks.
- Effectiveness: Higher response rates in treatment-resistant conditions.
- Long-Term Impact: Lasting symptom relief as opposed to traditional treatments.
Response and Remission Rates for Ketamine Therapy
Learn the efficacy of ketamine therapy in different settings
Research shows ketamine delivers rapid and sustained antidepressant effects in both single and multi-session treatments. It’s unique mechanism offers a novel approach in treating mental health and chronic pains.
Mechanisms of How Ketamine Works in the Brain
Targets specific brain regions and neural circuits
1
“Reset” the brain’s Default Mode Network (DMN), which is often overactive in people with mood disorders. By quieting this network, ketamine disrupts negative thought loops and allows the brain to form new, healthier patterns—like a mental reboot.
2
Creates a temporary sense of detachment, allowing reprocessing of traumatic memories. Treats: Suicidal Ideation, PTSD, OCD, Existential Distress
3
Creates a temporary sense of detachment, allowing reprocessing of traumatic memories. Treats: Suicidal Ideation, PTSD, OCD, Existential Distress
4
Promotes brain repair and growth by boosting brain-derived neurotrophic factor (BDNF). Treats: Depression, PTSD, Suicidal Ideation
5
Enhances synaptic plasticity by increasing glutamate activity and strengthening neural connections. Treats: Major Depressive Disorder (MDD), Treatment-Resistant Depression (TRD), PTSD, Anxiety, Bipolar Disorder
6
Reduces inflammation in the brain caused by stress or trauma. Treats: Depression, Anxiety, PTSD, Neurogenic Pain (e.g., Fibromyalgia, CRPS)
7
Enhances serotonin, dopamine, and endogenous opioid activity to regulate mood and relieve pain. Treats: Chronic Pain (e.g., CRPS, Neuropathic Pain), Depression, Anxiety
Is Ketamine Therapy the Right Treatment for You?
Are you answering “yes” to the following conditions?
Frequently asked questions
Why AVYIA in-home IV ketamine?
-
- AVYIA delivers a ground-breaking mental health treatment straight to your home, administered by doctors and health care providers.
- Ketamine is a potential paradigm shift in the treatment of mental health disorders.
- Ketamine starts working on day one for many, leading to complete resolution of mental health disorders by the end of the treatment program.
- Our ketamine therapy is vetted by the latest medical research and science.
- Ketamine is safe! It has a 50+ year safety track record.
- Our doctors and staff are committed to the highest standards of patient care and safety.
What is Ketamine?
- Ketamine is a “game-changer” medicine that provides immediate and long-lasting improvements in mental health disorders. Its effectiveness and safety record has been supported by robust medical studies.
- Ketamine is both a sedative and a dissociative psychedelic. It was originally used as an anesthetic, but recently found to produce amazing results in the treatment of mental health disorders.
- Recognized by the World Health Organization as an essential medicine.
- Developed in the 1950s and 1960s, approved by the FDA in 1970.
Is Ketamine therapy safe?
- AVYIA’s ketamine therapy and infusion treatments are very safe. We follow the latest medical guidelines and scientific research.
- Misuse of ketamine while under a clinician’s care is unlikely, especially with the low dosages that are used to treat mental health disorders.
- Ketamine has been stigmatized as a street drug for its psychedelic effects, known as “Special K,” but research has shown that low dose ketamine is incredibly safe, effective, and long-lasting.
- Ketamine misuses are in doses 5-10x more than the recommended medical doses used in anesthesia. Oftentimes serious side effects are associated with such dangerous doses including, ketamine-induced cystitis, a condition that affects the bladder.
- AVYIA works with several reputable pharmacies in the U.S. to prescribe and treat our patients.
When will I start feeling better
- Symptom relief may start within minutes of an initial IV infusion of ketamine therapy. For others, noticeable relief from symptoms may not start after a few sessions.
- Studies have shown that repeated doses of IV ketamine therapy work best. For the maximum effectiveness and the longest lasting effects, we recommend 6 IV sessions of ketamine therapy over a 3-week period.
- Relief of symptoms from microdosing ketamine is typically slower when compared to an IV treatment, however, some patients have reported noticeable symptom improvements within the first few days of starting microdosing.
What are Ketamine’s side effects?
- Ketamine side effects are generally mild and well tolerated.
- While side effects may differ from patient to patient, the most common side effects are brief elevations in blood pressure and nausea. Nausea can be easily treated with antiemetics, or anti-nausea medications on the spot. Blood pressure elevations are short lived and normalize soon after the ketamine treatment if completed.
- We ask that a responsible adult of the patient’s choosing to be close by during each ketamine therapy session. Patients should not drive themselves home from an IV or intranasal treatment due to possible drowsiness and dissociation after a treatment session.
