| Method |  Intravenous Infusion (IV) | Intramuscular Injection (IM) | Intranasal Spray | Sublingual Rapid Dissolve Tablet |
|---|
|
Route |  Direct administration into a vein | Injection into the muscle | Administration by inhaling a spray into the nostrils | Under the tongue absorption through the membranes of the mouth |
|
Treatment Program | 6 times in 2-4 weeks | 8 times in 4-6 weeks | 8 times in 4-6 weeks | Daily or intermittent use over multiple months |
|
Dosage |  Individually tailored sub-anesthetic amount enough to induce dissociative effect | Individually tailored sub-anesthetic amount enough to induce dissociative effect | Individually tailored sub-anesthetic amount enough to induce dissociative effect | Individually tailored lower than macro-dosing standard, typically not to induce dissociative effect |
|
Bioavailability | 100% | 93% | 40-50% | 25-40% |
|
Onset of Action | 1 min | 5 mins | 15 mins | 10-20 mins |
|
Strategy | Fully controllable titration of dosing to achieve optimal therapeutic effect in the least number of sessions | Uncontrollable dosing to achieve intense therapeutic effect in a few numbers of session | Controllable dosing to achieve good therapeutic effect in a few numbers of sessions | Collaborative managed low dosage treatment designed for long-term maintenance in sustaining ketamine’s therapeutic effect |
|
Effects & Experience | May induce profound psychedelic effect of dissociation or “out of body experience | May induce profound but short psychedelic effect of dissociation or “out of body experience” | May induce psychedelic effect of dissociation or “out of body experience” | Typically, no trigger significant dissociative effect, but still provide antidepressant and antianxiety experience |
|
Monitoring | Under the supervision of a medical provider each session | Under the supervision of a medical provider each session | Under the supervision of a medical provider each session | Self-administer under the direction of a medical provider |
|
Integration Therapy | Recommended | Recommended | Recommended | Optional |
|
Price | $3000 for 6 dosing sessions | $3600 for 8 dosing sessions | $3600 for 8 dosing sessions | Starting at $129 per month* |
|
Booster (as needed) | $499 per session | $449 per session | $429 per session | No booster necessary |
|
Appointment | Schedule | Schedule | Schedule | Schedule |
Intravenous Infusion (IV)
Intramuscular Injection (IM)
Intranasal Spray
Sublingual Rapid Dissolve Tablet
Direct administration into a vein
Injection into the muscle
Administration by inhaling a spray into the nostrils
Under the tongue absorption through the membranes of the mouth
6 times in 2-4 weeks
8 times in 4-6 weeks
Daily or intermittent use over multiple months
Individually tailored sub-anesthetic amount enough to induce dissociative effect
Individually tailored lower than macro-dosing standard, typically not to induce dissociative effect
1 min
5 mins
15 mins
10-20 mins
Fully controllable titration of dosing to achieve optimal therapeutic effect in the least number of sessions
Uncontrollable dosing to achieve intense therapeutic effect in a few numbers of session
Controllable dosing to achieve good therapeutic effect in a few numbers of sessions
May induce profound psychedelic effect of dissociation or “out of body experience
Under the supervision of a medical provider each session
Self-administer under the direction of a medical provider
Recommended
Optional
$3000 for 6 dosing sessions
$499 per session
$429 per session
Schedule