Ketamine research

Three Infusions, Eleven Days: What the Bio-K Study Found in Real-World Clinics
The Bio-K study gave three ketamine infusions to 74 people with severe treatment-resistant depression at four U.S. clinics. About half reached remission, and early response predicted who would.

Ketamine and Alcohol Recovery: What the KARE Trial Is Teaching Researchers
A UK trial paired ketamine infusions with therapy for people with alcohol use disorder. A 2026 analysis found the benefit did not depend on how intense the psychedelic experience was.

Ketamine or ECT? A Follow-Up Study Shows Who Benefits From Which
A 2024 follow-up to the ELEKT-D trial looked at 365 patients to see who did better with ketamine and who did better with ECT. Severity and setting made the difference.

When Ketamine Did Not Beat the Comparison: Lessons From the KARMA-Dep 2 Trial
A 2025 trial in JAMA Psychiatry found that adding ketamine infusions to inpatient depression care worked no better than an active comparison drug. What it means, and what it does not.
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