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Ketamine research

DepressionTRDNovember 13, 2026

Three Infusions, Eleven Days: What the Bio-K Study Found in Real-World Clinics

The Bio-K study gave three ketamine infusions to 74 people with severe treatment-resistant depression at four U.S. clinics. About half reached remission, and early response predicted who would.

ResearchTherapyNovember 13, 2026

Ketamine and Alcohol Recovery: What the KARE Trial Is Teaching Researchers

A UK trial paired ketamine infusions with therapy for people with alcohol use disorder. A 2026 analysis found the benefit did not depend on how intense the psychedelic experience was.

DepressionTRDNovember 13, 2026

Ketamine or ECT? A Follow-Up Study Shows Who Benefits From Which

A 2024 follow-up to the ELEKT-D trial looked at 365 patients to see who did better with ketamine and who did better with ECT. Severity and setting made the difference.

DepressionResearchNovember 13, 2026

When Ketamine Did Not Beat the Comparison: Lessons From the KARMA-Dep 2 Trial

A 2025 trial in JAMA Psychiatry found that adding ketamine infusions to inpatient depression care worked no better than an active comparison drug. What it means, and what it does not.

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