Yes. Microdosing has been used to treat migraines as well as chronic pain. Microdosing on a daily basis might be a viable option for individuals experiencing refractory chronic migraines, for whom traditional painkillers and preventive medications are usually ineffective. Those suffering from headaches on a daily or near-daily basis may find significant benefits from microdosing, as it offers patients greater control in managing their own dosing regimen to better control their symptoms.

There are many types of migraines and headache types: Migraine without aura, migraine with aura, migraine without head pain, hemiplegic migraine, retinal migraine, chronic migraine, abdominal migraine, ice pick headache, cluster headache, cervicogenic headache, thunder-clap head ache, tension headaches, and many other headaches as a result of other ailments.

Immediately after ketamine treatment, it is common to feel a little tipsy, uneasy, or nauseous. Also feeling exhausted is not an uncommon symptom either. Although some individuals are able to resume their work routine 1-2 hours after treatment, we recommend taking the remainder of the day off following your initial visit to assess how you feel.  You should not drive immediately after an IV or intranasal infusion as you are under the influence and likely impaired.

Patients microdosing ketamine typically do not have any impairment from their ketamine, but should still exercise good judgement with respect to driving and operating dangerous tools or equipment.

Yes, “off-label” use of ketamine for treating migraines and other disorders is perfectly legal.  In fact, 1/5 to 1/4 of all prescription medications are prescribed off-label.  The term off-label use refers to the use of a medication for a purpose other than what it was originally approved for by the regulatory authorities. Ketamine was initially approved by the U.S. Food and Drug Administration (FDA) for use as an anesthetic and analgesic medication.

Healthcare providers are legally allowed to prescribe medications, including ketamine, for off-label uses if they believe it is medically appropriate and in the best interest of the patient. Off-label use is common in medicine, and it allows healthcare professionals to explore alternative treatments for various conditions, especially when traditional treatments have been ineffective or unavailable.

AVYIA’s low dose ketamine is well-tolerated and safe when used under the supervision of a medical provider.

Side effects are generally mild and well tolerated. Symptoms may vary from patient to patient, but common side effects are slight elevations in blood pressure and nausea. Nausea can be easily treated with antiemetics or anti-nausea medications on the spot.

Psychedelic experiences and dissociative effects may occur in the doses we give for IV and intranasal treatments. This is also known an out-of-body experience, or going on “a trip.” After completion of a treatment, some patients have reported false epiphanies, such as “knowing the meaning of life.”

All these effects are typically short lasting once the treatment is over. Patient’s are back to their baseline the next day typically, but we still recommend exercising caution. Patients should not drive while under the influence of ketamine, nor should they make rash decisions on false epiphanies. Finally, AVYIA requests patients have a responsible adult present to monitor patients after the healthcare providers finish their monitoring efforts.