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Ketamine for acute suicidal ideation. An emergency department intervention: A randomized, double-blind, placebo-controlled, proof-of-concept trial.

Domany Y, Shelton RC, McCullumsmith CB. Ketamine for acute suicidal ideation. An emergency department intervention: A randomized, double-blind, placebo-controlled, proof-of-concept trial. Depress Anxiety. 2020 Mar;37(3):224-233. doi: 10.1002/da.22975. Epub 2019 Nov 16. PMID: 31733088. Highlights: A single dose of IV ketamine produced effective and rapid reductions in suicidal ideation in as little as 90 minutes. 88% […]

Ketamine for Treatment-Resistant Mood Disorders

ketamine Nasal spray bottle

Highlights: Strong evidence supports the rapid, although temporary, antidepressant effects of a single intravenous ketamine infusion for treatment-resistant major depressive disorder (MDD) and bipolar depression. Intravenous ketamine administration for treatment-resistant depression (TRD) is generally safe and well tolerated when administered by trained professionals. Ketamine research is transforming our understanding of the pathophysiology of mood disorders […]

Ketamine for Treatment-Resistant Mood Disorders.

Park LT, Falodun TB, Zarate CA Jr. Ketamine for Treatment-Resistant Mood Disorders. Focus (Am Psychiatr Publ). 2019 Jan;17(1):8-12. doi: 10.1176/appi.focus.20180030. Epub 2019 Jan 7. PMID: 31975953; PMCID: PMC6493154.   Highlights: Strong evidence supports the rapid, although temporary, antidepressant effects of a single intravenous ketamine infusion for treatment-resistant major depressive disorder (MDD) and bipolar depression. Intravenous […]

Improvement in suicidal ideation after repeated ketamine infusions.

Albott, C. S., Lim, K. O., Forbes, M. K., Thuras, P., Wels, J., Tye, S., & Shiroma, P. (2019). 3525 Improvement in suicidal ideation after repeated ketamine infusions: Journal of Clinical and Translational Science, 3(s1), 46–46.   Highlights: This study showed significant improvement in suicidal ideation within 24 hours of the first ketamine infusion therapy […]