ClickCease

Is Ketamine Safe for Mental Health Treatment?

Exploring the Safety Profile of Ketamine Compared to Other Medications   Introduction: Is ketamine safe for mental health treatment? Many individuals have questions and concerns about the safety of using ketamine as a therapeutic option. In this blog, we will delve into the safety record of ketamine, compare it to other commonly prescribed mental health […]

Unlocking Psychedelics: How Celebrities Are Rewriting the Narrative

From Elon Musk to Amanda Feilding, A Look at the Celebrities Changing the Psychedelic Landscape   Introduction: In recent years, the world has witness a significant shift in the perception of psychedelics, and this transformation owes much to the influence of celebrities. From Elon Musk’s candid discussions about using ketamine to Amanda Feilding’s advocacy for […]

Hangover Survival Guide: Causes, Remedies, and Impact on Health

Alcohol is widely consumed in the world for social enjoyment, relaxation and emotional coping. In many cultures, alcohol consumption is deeply ingrained in traditions, rituals, and social customs. However, it is also a leading contributor to substance abuse. In US and Europe, more than half of the population consumes alcohol now and then. However, about […]

Sustained rescue of prefrontal circuit dysfunction by antidepressant-induced spine formation

R.N. Moda-Sava, M.H. Murdock, P.K. Parekh, R.N. Fetcho, B.S. Huang, T.N. Huynh, J. Witztum, D.C. Shaver, D.L. Rosenthal, E.J. Alway, K. Lopoz, Y. Meng, L. Nellissen, L. Grosenick, T.A. Milner, K.Deisseroth, H. Bito, H. Kasai, C. Liston.  Sustained rescue of prefrontal circuit dysfunction by antidepressant-induced spine formation.  2019 Apr 12; Vol 364, Issue 6436. DOI: […]

Science and Lifestyle Strategies for Healthy Aging

It is a well-known fact that no two people age at the same speed. Some age faster and frequently experiences health issues. Others seem to live a relatively healthy and active life for long. Of course, genetics here play a role. However, lifestyle choices play a greater role in healthy aging. Surely, at least with […]

NAD+ IV Therapy Benefits: A Complete Guide to Anti-aging Therapy

Humans have sought the fountain of youth for ages. Though reversing chronological age might not be possible, reducing metabolic age is possible. Two people of the same chronological age have different health statuses. This is due to the difference in metabolic age.1 It is well-known that some people seem to age faster, others more slowly. […]

Dose-related effects of ketamine for antidepressant-resistant symptoms of posttraumatic stress disorder in veterans and active duty military: a double-blind, randomized, placebo-controlled multi-center clinical trial.

Abdallah, C.G., Roache, J.D., Gueorguieva, R. et al. Dose-related effects of ketamine for antidepressant-resistant symptoms of posttraumatic stress disorder in veterans and active duty military: a double-blind, randomized, placebo-controlled multi-center clinical trial. Neuropsychopharmacol. 47, 1574–1581 (2022). Highlights: The standard ketamine dose treated depression significantly more than placebo. Ketamine produced dose-related dissociative and psychotomimetic effects, which […]

(R)-Ketamine Rapidly Ameliorates the Decreased Spine Density in the Medial Prefrontal Cortex and Hippocampus of Susceptible Mice After Chronic Social Defeat Stress. Ketamine demonstrates neuroplasticity. Neuroplasticity is hypothesized to be a key component to mental health recovery.

Zhang J, Qu Y, Chang L, Pu Y, Hashimoto K. (R)-Ketamine Rapidly Ameliorates the Decreased Spine Density in the Medial Prefrontal Cortex and Hippocampus of Susceptible Mice After Chronic Social Defeat Stress. Int J Neuropsychopharmacol. 2019 Oct 1;22(10):675-679. doi: 10.1093/ijnp/pyz048. PMID: 31504547; PMCID: PMC6822137. Highlights: This study suggests that (R)-ketamine rapidly ameliorates the decreased spine […]

Ketamine Assisted Psychotherapy (KAP): Patient Demographics, Clinical Data and Outcomes in Three Large Practices Administering Ketamine with Psychotherapy.

Dore J, Turnipseed B, Dwyer S, Turnipseed A, Andries J, Ascani G, Monnette C, Huidekoper A, Strauss N, Wolfson P. Ketamine Assisted Psychotherapy (KAP): Patient Demographics, Clinical Data and Outcomes in Three Large Practices Administering Ketamine with Psychotherapy. J Psychoactive Drugs. 2019 Apr-Jun;51(2):189-198. doi: 10.1080/02791072.2019.1587556. Epub 2019 Mar 27. PMID: 30917760. Highlights: Our findings suggest […]

Antidepressant, mood stabilizing and procognitive effects of very low dose sublingual ketamine in refractory unipolar and bipolar depression.

Bipolar-Depressive-Episoide

Lara DR, Bisol LW, Munari LR. Antidepressant, mood stabilizing, and procognitive effects of very low dose sublingual ketamine in refractory unipolar and bipolar depression. Int J Neuropsychopharmacol. 2013 Oct;16(9):2111-7. doi: 10.1017/S1461145713000485. Epub 2013 May 20. PMID: 23683309. Highlights: According to patients’ reports, VLDS [very low dose sublingual] ketamine produced rapid, clear, and sustained effects, improving […]